Synthesis, spectral characterization, thermal and biological studies of lanthanide(Ⅲ) complexes of oxyphenbutazone

作     者：P.S.Binil M.R.Anoop K.R.Jisha S.Suma M.R.Sudarsanakumar 

作者机构：Department of Chemistry S.N.College Department of Chemistry M.G.College 

出 版 物：《Journal of Rare Earths》 (稀土学报（英文版）)

年 卷 期：2014年第32卷第1期

页      面：43-51页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：University of Kerala for the financial support 

主　　题：oxyphenbutazone lanthanide(III) complexes thermal study antimicrobial activity rare earths 

摘      要：Lanthanide（III） complexes of 4-butyl-1-（4-hydroxyphenyl）-2-phenyl-3,5-pyrazolidinedione （OPB） were prepared by ho-mogeneous precipitation. The solid complexes were characterized by elemental analysis, magnetic susceptibility data, molar conduc-tivity measurements and IR, UV-Vis, mass, 1H NMR and 13C NMR spectral methods. The thermal decomposition of the complexes under static air atmosphere was investigated by simultaneous TG/DTG at a heating rate of 10 °C/min. The final decomposition prod-ucts were found to be metal oxides. The spectroscopic data suggested that OPB acted as a bidentate, mono-ionic ligand coordinating through two carbonyl oxygens of the pyrazolidinedione ring. The kinetic and thermodynamic parameters such as activation energy, pre-exponential factor and entropy of activation for each step of the decomposition reactions were evaluated using Coats-Redfern and MacCallum-Tanner equations. The negative entropy values of the complexes indicated that the activated complexes had a more or-dered structure than the reactant and that the reactions were slower than normal. Investigations of antimicrobial activity of the com-pounds were carried out by the disk diffusion technique.