SPINDLY, ERECTA, and Its Ligand STOMAGEN Have a Role in Redox-Mediated Cortex Proliferation in the Arabidopsis Root

作     者：Hongchang Cui Danyu Konga Pengcheng Wei Yueling Hao Keiko U. Torii Jin Suk Lee Jie Li 

作者机构：Department of Biological Science Florida State University Tallahassee FL 32306-4295 USA Present address: Biotechnical Group Institute of Rice Research Anhui Agricultural Academy of Science 40# Nongke South RoadHefei Anhui 230031 China Howard Hughes Medical Institute Department of Biology University of Washington Seattle WA 98195-1800 USA 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2014年第7卷第12期

页      面：1727-1739页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 081705[工学-工业催化] 08[工学] 0817[工学-化学工程与技术] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0902[农学-园艺学] 090102[农学-作物遗传育种] 

基　　金：Funding for this work was from a set-up fund from the Florida State University (to H.C.). K.U.T. is an HHMI-GBMF investigator 

主　　题：SPY ERECTA STOMAGEN redox homeostasis ROS signaling abiotic stress cortex proliferation Arabidopsisthaliana. 

摘      要：Reactive oxygen species （ROS） are harmful to all living organisms and therefore they must be removed to ensure normal growth and development. ROS are also signaling molecules, but so far little is known about the mecha- nisms of ROS perception and developmental response in plants. We here report that hydrogen peroxide induces cortex proliferation in the Arabidopsis root and that SPINDLY （SPY）, an O-linked glucosamine acetyltransferase, regulates cortex proliferation by maintaining cellular redox homeostasis. We also found that mutation in the leucine-rich receptor kinase ERECTA and its putative peptide ligand STOMAGEN block the effect of hydrogen peroxide on root cortex proliferation. However, ERECTA and STOMAGEN are expressed in the vascular tissue, whereas extra cortex cells are produced from the endodermis, suggesting the involvement of intercellular signaling~ SPY appears to act downstream of ERECTA, because the spy mutation still caused cortex proliferation in the erecta mutant background. We therefore have not only gained insight into the mechanism by which SPY regulates root development but also uncovered a novel pathway for ROS signal- ing in plants. The importance of redox-mediated cortex proliferation as a protective mechanism against oxidative stress is also discussed.