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Clinical improvement in the therapy of aural keloids

Clinical improvement in the therapy of aural keloids

作     者:ZHANG Yan-ge CEN Ying LIU Xiao-xue YU Rong XU Xue-wen 

作者机构:Department of Burns and Plastic Surgery West China HospitalSichuan University Chengdu Sichuan 610041 China 

出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))

年 卷 期:2009年第122卷第23期

页      面:2865-2868页

核心收录:

学科分类:1002[医学-临床医学] 10[医学] 

主  题:keloid surgery radiotherapy, adjuvant ear 

摘      要:Background Keloids have a predilection for the aural region because of the special shape of the pinna. It is difficult to resect keloids entirely and maintain a satisfactory pinnal shape. Surgical excision in combination with radiotherapy is considered to be the most efficacious treatment available for severe keloids. This study was conducted to evaluate the treatment of aural keloids with intralesional excision and immediate postoperative adjuvant radiotherapy. Methods Forty-six patients with a combined total of 74 aural keloids were treated by intralesional excision and immediate postoperative adjuvant radiotherapy. All patients received a total dose of 20 Gy in 10 consecutive days. The time interval between keloid excision and delivery of the first radiotherapy fraction was 〈24 hours in all cases. The median follow-up was 2.2 years. Results Twenty-nine patients with 48 keloids (64.9%) were highly satisfied with their outcome, and were rated as good by the surgeon. Six patients with 12 keloids (16.2%) showed general satisfaction but wanted aesthetic refinement, and these patients were rated as fair by the surgeon. Three patients with four keloids (5.4%) showed no evidence of recurrence after surgery, but disliked the result because of the discoloration and irregularity of the scar surface. These patients were rated as poor by the surgeon. Partial recurrence occurred in 8 patients with 10 keloids (13.5%). No major complications were observed. Conclusion Intralesional excision and immediate postoperative adjuvant radiotherapy is well tolerated and very effective in Dreventing recurrence of aural region keloids.

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