the 20GD Superfamily： Emerging Functions in Plant Epigenetics and Hormone Metabolism

作     者：Riad Nadi Eduardo Mateo-Bonmati Lucia Juan-Vicente Jose Luis Micol 无

作者机构：Instituto de Bioingenieria Universidad Miguel Hern&ndez Campus de Elche 03202 Elche Spain 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2018年第11卷第10期

页      面：1222-1224页

核心收录：

学科分类：0710[理学-生物学] 12[管理学] 120203[管理学-旅游管理] 071010[理学-生物化学与分子生物学] 1202[管理学-工商管理] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

基　　金：supported by grants from the Ministerio de Economia, Industria y Competitividad of Spain the Generalitat Valenciana to J.L.M 

主　　题：DEMETHYLASE DIVERSITY 

摘      要：The 2-oxoglutarate and Fe （ll）-dependent dioxygenase （2OGD） superfamily includes oxidative enzymes with an active site con- taining two histidines and （in most cases） one aspartic or glutamic acid residue. This conserved motif is termed the 2-His-1-carboxylate facial triad, chelates iron, and is housed within a double-stranded β-helix fold, also known as the DSBH, jelly-roll, cupin, or Jumonji C fold （Martinez and Hausinger, 2015）. The reactions catalyzed by 2OGDs （also called 2ODDs, 2ODQs, and 2OGXs） include but are not limited to demethylation, demethylenation, hydroxytation, halogenation, desaturation, ring cleavage, ring closure, and epimerization （Farrow and Facchini, 2014）.