Comparison of anterior segment optical coherence tomography findings in acanthamoeba keratitis and herpetic epithelial keratitis

作     者：Young Min Park Jong Soo Lee Ji-Myong Yoo Jong Moon Park Seong-Wook Seo In-Young Chun Seong Jae Kim 

作者机构：Department of Ophthalmology School of Medicine Gyeongsang National University Jinju 52727 South Korea Gyeongsang National University Changwon HospitalSamjeongja-ro Seongsan-gu Changwon-si Gyeongsangnamdo 51472 South Korea Department of Ophthalmology School of Medicine Pusan National University and Medical Research Institute Pusan National University Hospital Pusan 49241 South Korea Institute of Health Science Gyeongsang National UniversityJinju 52727 South Korea 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2018年第11卷第8期

页      面：1416-1420页

核心收录：

学科分类：1002[医学-临床医学] 0806[工学-冶金工程] 08[工学] 

基　　金：Supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science  ICT & Future Planning (No.NRF-2015R1C1A1A02037702) 

主　　题：acanthamoeba optical coherence tomography herpes herpetic keratitis 

摘      要：This study is to investigate the characteristic features of Acanthamoeba keratitis（AK） that differentiating it from herpetic epithelial keratitis（HEK） using anterior segment optical coherence tomography（AS-OCT）. Medical records of three eyes of each AK and herpetic keratitis who had AS-OCT examination were reviewed in this study. Slitlamp biomicroscopy and AS-OCT was performed on the initial visit and on every follow-up visits in all patients. In all three AK cases, reflective bands in the corneal stroma that correspond to the area of radial keratoneuritis were observed. The depth of the reflective bands varied in each case. After AK treatment, slit-lamp biomicroscopy confirmed that radial keratoneuritis had resolved and AS-OCT confirmed that reflective bands in the corneal stroma had also disappeared in all patients. Unlike the AS-OCT results found in AK, highly reflective HEK lesions were observed only in the subepithelial area, not in the stroma. AS-OCT seems to be helpful analyzing the specific depth of the lesion which enables to distinguish AK from HEK.