Ultrasound Assessraent of Intima-media Thickness and Diameter of Carotid Arteries in Patients Undergoing Hemodialysis or Renal Transplantation

作     者：Zhao-jun Li Lian-fang DU Yan QIN Ji-bin LIU Xiang-hong LUO 

作者机构：Department of UltrasoundShanghai General Hospital Shanghai Jiao Tong University Shanghai 200080 China Department of UrologyShanghai General Hospital Shanghai Jiao Tong University Shanghai 200080 China Department of Radiology Thomas Jefferson University Philadelphia 19107 USA Department of Echocardiography Shanghai General Hospital Shanghai Jiao Tong University Shanghai 200080 China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2018年第38卷第4期

页      面：727-733页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100211[医学-妇产科学] 10[医学] 

基　　金：Shanghai Science and Technology Committee Fund [15411969100, 16411969300] Interdisciplinary Program of Shanghai Jiao Tong University [YG2015MS28] Shanghai Health and Family Planning Commission Fund [201440290, 201640043] Three-year Plan for Clinical Skills and Innovation in Municipal Hospitals [16CR3105B] Technology Transfer Project of Science & Technology Department, Shanghai Jiao Tong University School of Medicine [ZT201710, ZT201711] 

主　　题：ultrasonic radiofrequency tracking renal transplantation arteriosclerosis carotid intima-media thickness age 

摘      要：Renal transplant （RT） recipients have a high risk of developing cardiovascular diseases. However, the effects of renal transplantation on the development of arteriosclerosis have been controversial. The carotid intima-media thickness （CIMT） and diameter （CD） are important indicators of vascular remodeling and arteriosclerosis. In this study, 31 patients with hemodialysis （HD）, 31 RT recipients and 84 age- and gender-matched control subjects were enrolled. Their CIMT and CD were measured by ultrasonic radiofrequency tracking, and the linear regression models and Z test were used to identify the progression of arteriosclerosis and the risk factors. Compared with HD group, RT group had significantly lower CIMT and CD. CIMT was found to be associated with age, body weight, resistance index and diastolic velocity, while CD was associated significantly with age, body weight, pulsatility index, end diastolic velocity and diastolic blood pressure （DBP）, respectively. The correlation curves between CIMT and age showed the slopes of curves were decreased successively in control, RT and HD groups, and the curves between CD and age showed the slopes were decreased in order of RT 〉 control 〉 HD groups. It was concluded that CIMT and CD were significantly correlated with age in RT and moderately with age in HD patients. RT could reduce the progress of arteriosclerosis in patients with end-stage renal disease.