Plasma antioxidant capacity, sexual and thyroid hormones levels, sperm quantity and quality parameters in stressed male rats received nano-particle of selenium

作     者：Rezaeian-Tabrizi M Sadeghi AA 

作者机构：Department of Animal ScienceScience and Research BranchIslamic Azad UniversityTehranIran 

出 版 物：《Asian pacific Journal of Reproduction》 (亚太生殖杂志（英文版）)

年 卷 期：2017年第6卷第1期

页      面：32-37页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Antioxidant capacity Oxidative stress Nano-selenium Sperm parameters Hormone Rat 

摘      要：Objective:To evaluate the effects of nano-particle of selenium (nSe) on plasma antioxidant capacity, sexual and thyroid hormones and spermatogenesis in male rats exposed to oxidative ***:Forty rats were randomly divided into four treatments with ten replicates. Treatment groups were: C, the control group received normal saline as gavage and injection (i.p.);OS, received tert-butyl hydroperoxide (0.2 mmol/kg body weight) for inducing oxidative stress;nSe, received nSe (0.3 mg/kg body weight) as gavage, and OS+nSe, received tert-butyl hydroperoxide and nSe. All groups were treated for 28 d and administrations were done each 48 ***:Oxidative stress decreased and gavage of nSe to stressed rats increased the antioxidant capacity and activities (P0.05) between rats exposed to oxidative stress and those in the control group for sperm quantity and quality. Gavage of nSe to stressed rats had no effect (P0.05) on the sperm parameters, except increased viability and progressive ***:Nano-particle of Selenium administration in stressed rats could ameliorate the negative effects of oxidative stress on the antioxidant capacity and activities, but not on the quantity and quality parameters of sperm.