Novel SPECT Technologies and Approaches in Cardiac Imaging

作     者：Piotr Slomka Guang-Uei Hung Guido Germano Daniel S.Berman 

作者机构：Departments of Imaging and MedicineCedars-Sinai Medical CenterLos AngelesCAUSA Department of Nuclear MedicineChang Bing Show Chwan Memorial HospitalChanghuaTaiwan 

出 版 物：《Cardiovascular Innovations and Applications》 (心血管创新与应用（英文）)

年 卷 期：2016年第2卷第B12期

页      面：31-46页

学科分类：10[医学] 

基　　金：National Heart, Lung, and Blood Institute/National Institutes of Health (NHLBI/NIH)United States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Heart Lung & Blood Institute (NHLBI) [R01HL089765] NATIONAL HEART, LUNG, AND BLOOD INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Heart Lung & Blood Institute (NHLBI) [R01HL089765] Funding Source: NIH RePORTER 

主　　题：myocardial perfusion imaging single photon emission computed tomography fast myocardial perfusion single photon emission computed tomography quantifi cation low dose stress only 

摘      要：Recent novel approaches in myocardial perfusion single photon emission CT(SPECT)have been facilitated by new dedicated high-effi ciency hardware with solid-state detectors and optimized *** protocols include very low-dose(1 mSv)stress-only,two-position imaging to mitigate attenuation artifacts,and simultaneous dual-isotope *** correction can be performed by specialized low-dose systems or by previously obtained CT coronary calcium *** protocols using CT angiography have been *** quality improvements have been demonstrated by novel reconstructions and motion *** SPECT acquisition facilitates dynamic fl ow and early function *** processing algorithms have become automated with virtually unsupervised extraction of quantitative imaging *** automation facilitates integration with clinical variables derived by machine learning to predict patient outcome or *** this review,we describe new imaging protocols made possible by the new hardware *** also discuss several novel software approaches for the quantifi cation and interpretation of myocardial perfusion SPECT scans.