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Sperm donation and its application in,China: a 7-year multicenter retrospective study

Sperm donation and its application in,China: a 7-year multicenter retrospective study

作     者:Ping Ping Wen-Bing Zhu Xin-Zong Zhang Yu-Shan Li Quan-Xian Wang Xiao-Rong Cao Yong Liu Hui-Li Dai Yi-Ran Huang Zheng Li 

作者机构:Department of Urology Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai Human Sperm Bank Shanghai 200001 China Institute of Human Reproduction and Stem Cell Engineering Human Sperm Bank Central South University Changsha 410078 China Zhejiang Institute of Planned Parenthood Research and Zhejiang Human Sperm Bank Hangzhou 310012 China Human Sperm Bank The Third Affiliated Hospital of Zhengzhou University Zhengzhou 450052 China 

出 版 物:《Asian Journal of Andrology》 (亚洲男性学杂志(英文版))

年 卷 期:2011年第13卷第4期

页      面:644-648页

核心收录:

学科分类:090603[农学-临床兽医学] 02[经济学] 0202[经济学-应用经济学] 1002[医学-临床医学] 09[农学] 0906[农学-兽医学] 020202[经济学-区域经济学] 

基  金:Shanghai Scientific Committee Program Shanghai Jiao Tong University Med-Science Cross Research Foundation Science,Technology Commission of Shanghai Municipality Program 

主  题:artificial insemination with donor sperm donor in vitro fertilization sperm donation 

摘      要:Sperm donation in China is different from that in other countries due to cultural, social and political factors. This research presents the current status of sperm donation in China s Mainland and highlights some problems. Between January 2003 and December 2009, 19 471 sperm donors were screened totally and 6467 donors (33.2%) were recruited. The primary reasons for non-recruitment were either inadequate semen parameters (55.0%) or positive results for sexually transmitted diseases (7.9%). There were 327 (1.7%) qualified donors who withdrew from the program because of frustration related to failed semen parameters, participation merely for free medical tests or job transfer. A questionnaire investigating donor intention, as well as other concerns associated with sperm donation, was distributed to 516 potential donors. All potential donors indicated their primary motivation as altruism, while 90.9% mentioned monetary reward as a second motivating factor. Approximately 93.4% of donors expressed some apprehension about the risk of consanguineous mating and the protection of their identity. Over the past 7 years, 488 389 vials of donors' semen have been cryopreserved. In 36 438 artificial insemination with donor sperm (AID) cycles, the clinical pregnancy rate was 23.9% and the live birth rate was 16.6%, In 7148 in vitro fertilization cycles, the clinical pregnancy rate was 45.8% and the live birth rate was 35.2%. Human sperm banks have been strictly monitored to ensure that each sperm donor can only impregnate five women nationwide. There is still a large gap between the supply and demand for sperm donation which may be solved by updated guidelines.

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