视盘损害相关分级、杯盘比和Heidelberg视网膜断层摄影在青光眼诊断中的作用比较

作     者：Danesh-Meyer H. V. Gaskin B. J. Jayusundera T. 刘瑛(译) 

作者机构：Department of Ophthalmology University of Auckland Auckland New Zealand 不详 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2006年第2卷第9期

页      面：32-33页

学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学] 

主　　题：临床诊断价值 青光眼患者 视盘损害 断层摄影 杯盘比 视网膜 HRT-Ⅱ Anderson 

摘      要：Aim:To evaluate the relative diagnostic strength of cup to disc(C/D)ratio,clinical disc damage likelihood scale(DDLS),a new clinical method of documenting glaucomatous optic disc changes,and Heidelberg retina tomograph(HRT-II)in patients with glaucoma,glaucoma suspects,and normal ***:Consecutive observational case series.110 eyes from 110 patients categorised as glaucoma,glaucoma suspect,or normal were examined clinically to grade the DDLS ***-II examination was performed by an examiner masked to the clinical examination *** disc parameters and Moorfields regression analysis findings were *** of the optic disc were examined independently by two glaucoma specialists in masked fashion to determine the C/D *** SITA Standard 24-2 visual fields were obtained within 3 months of HRT-II and clinical *** each patient,the eye with the worse mean deviation of the visual field test was enrolled in the study,and each field was additionally graded by the four level Hodapp-Parrish-II-Anderson *** and sensitivity were calculated by receiver operating characteristic(ROC)***:Mean patient age was 58 years(SD 13.3)with 45 glaucoma patients,23 glaucoma suspects,and 42 *** mean deviation on Humphrey visual field assessment using SITA-Standard was-4.95 D(SD 5 D)Clinical examination using DDLS had the best predictive power with an area under the ROC curve value of 0.95 when glaucoma patients and suspects were separated from borderline or *** was followed by clinical examination of C/D ratio(0.84),and HRT-II Moorfields analysis(0.68).The order of diagnostic strength did not change when definite glaucoma was compared to borderline and ***:The DDLS grading performs well compared to C/D ratio and HRT-II *** to disc diameter and to rim width may increase the value of clinical optic disc examination.