SOLID PHASE SYNTHESIS AND CD SPECTRUMSTUDY OF ＂ZINC－FINGER＂ PEPTIDE RELATED TO CAULIMOVIRUS

作     者：Hong JI Ruo Heng ZHANG Met Cheng SHAO(Institute of Physical Chemistry, Beijing University,Beijing 100871) 

作者机构：Beijing Univ Dept Chem Phys Beijing 100871 Peoples R China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1995年第6卷第6期

页      面：463-464页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 070301[理学-无机化学] 

主　　题：CD SPECTRUMSTUDY SYNTHESIS AND CAULIMOVIRUS 

摘      要：Caulimovirus contains a highly conserved,low molecular weight protein which has a zinc finger-like motif Cys×2Cys×4His×4Cys in common with the animal *** zinc finger-like peptide of caulimovirus(17 residues)was synthesized by solid phase method for structural *** standard HF treatment and low-high HF treatment were used to cleave the peptide from the *** peptide cleaved with low-high HF had higher purity and yield than that with standard HF *** dichroic spectroscopy indicates that the peptide exhibits a random coil conformation in the absence of zinc but appears to form an ordered structure in the presence of zinc.