Corrosion behavior and cytocompatibility of fluoride-incorporated plasma electrolytic oxidation coating on biodegradable AZ31 alloy
作者机构：State Key Laboratory of High Performance Ceramics and Superfine MicrostructureShanghai Institute of CeramicsChinese Academy of SciencesShanghai200050P.R.China
出 版 物：《Regenerative Biomaterials》 (再生生物材料（英文版）)
年 卷 期：2017年第4卷第1期
页 面：1-10页
核心收录：
学科分类：08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）]
基 金：Financial support from the National Science Foundation for Distinguished Young Scholars of China(51525207) National Natural Science Foundation of China(31570973) Shanghai Committee of Science and Technology,China(14XD1403900,15441904900)are acknowledged
主 题：Mg alloy fluoride corrosion resistance cytocompatibility
摘 要：Fluoride-incorporated plasma electrolytic oxidation(PEO)coating was fabricated on biodegradable AZ31 *** surface morphologies and phases were investigated by scanning electron microscopy and X-ray *** effect of fluoride incorporation in coatings on corrosion behaviour was investigated in simulated body fluid and in vitro cytocompatibility of the coatings was also studied by evaluating cytotoxicity,adhesion,proliferation and live-dead stain of osteoblast cells(MC3T3-E1).Furthermore,the corrosion morphologies in vivo were *** results showed that the fluoride could be incorporated into the coating to form MgF2 *** vitro and in vivo degradation tests revealed that the corrosion resistance of the coating could be improved by the incorporation of fluoride,which may attribute to the chemical stability of MgF2 ***,good cytocompatibility of fluoride-incorporated coating was confirmed with no obvious cytotoxicity,enhanced cell adhesion and ***,when the fluoride content was high,a slight inhibition of cell growth was *** results indicate that although fluoride incorporation can enhance the corrosion resistance of the coatings,thus resulting a more suitable environment for cells,the high content of fluoride in the coating also kill cells ascribed to the high released of *** the content of fluoride is well controlled,the PEO coating with MgF2 phase is a promising surface modification of Mg alloys.
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