Base-excision repair and beyond—A short summary attributed to scientific achievements of Tomas Lindahl, Nobel Prize Laureate in Chemistry 2015

作     者：Shuangli Mi Arne Klungland Yun-Gui Yang 

作者机构：Key Laboratory of Genomic and Precision Medicine Collaborative Innovation Center of Genetics and Development CAS Center for Excellence in Molecular Cell Science Beijing Institute of Genomics Chinese Academy of Sciences Department of Microbiology Division of Diagnostics and Intervention Institute of Clinical Medicine Oslo University HospitalRikshospitalet Department of Molecular Medicine Institute of Basic Medical Sciences University of Oslo 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2016年第59卷第1期

页      面：89-92页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

主　　题：碱基切除修复 诺贝尔奖得主 托马斯 科学成果 归结 化学 科学生涯 修复机制 

摘      要：Tomas Lindahl contributed his scientific career to unveiling fundamental mechanisms of DNA decay and repair.He made several ground-breaking discoveries on genome instability,novel DNA repair activities and pathways,and disease association.The 2015 Nobel Prize in Chemistry was awarded jointly to Tomas Lindahl,Paul Modrich and Aziz Sancar for their mechanistic studies of DNA repair.Their findings