Novel Magnesium Alloys Developed for Biomedical Application:A Review

作     者：Nan Li Yufeng Zheng 

作者机构：State Key Laboratory for Turbulence and Complex System and Department of Materials Science and EngineeringCollege of EngineeringPeking University 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2013年第29卷第6期

页      面：489-502页

核心收录：

学科分类：081203[工学-计算机应用技术] 08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0835[工学-软件工程] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：supported by the National Basic Research Program of China(973 Program)(Nos.2012CB619102 and 2012CB619100) the National Science Fund for Distinguished Young Scholars(No.51225101) the National Natural Science Foundation of China(No.31170909) the Research Fund for the Doctoral Program of Higher Education(No.20100001110011) the Natural Science Foundation of Heilongjiang Province(No. ZD201012) the Project for Supervisor of Excellent Doctoral Dissertation of Beijing(No.20121000101) the Guangdong Province Innovation R&D Team Project(No.201001 C0104669453) 

主　　题：Biomaterials Magnesium alloys Biodegradation Mechanical property Biocompatibility 

摘      要：There is an increasing interest in the development of magnesium alloys both for industrial and biomedical applications. Industrial interest in magnesium alloys is based on strong demand of weight reduction of transportation vehicles for better fuel efficiency, so higher strength, and better ductility and corrosion resistance are required. Nevertheless, biomedical magnesium alloys require appropriate mechanical properties, suitable degradation rate in physiological environment, and what is most important, biosafety to human body. Rather than simply apply commercial magnesium alloys to biomedical field, new alloys should be designed from the point of view of nutriology and toxicology. This article provides a review of state-of-the-art of magnesium alloy implants and devices for orthopedic, cardiovascular and tissue engineering applications. Advances in new alloy design, novel structure design and surface modification are overviewed. The factors that influence the corrosion behavior of magnesium alloys are discussed and the strategy in the future development of biomedical magnesium alloys is proposed.