Toxic effects of enrofloxacin on Scenedesmus obliquus

作     者：Hongwei QIN Liufang CHEN Nan LU Yahui ZHAO Xing YUAN 

作者机构：School of Urban and Environmental ScienceNortheast Normal UniversityChangchun 130024China 

出 版 物：《Frontiers of Environmental Science & Engineering》 (环境科学与工程前沿（英文）)

年 卷 期：2012年第6卷第1期

页      面：107-116页

核心收录：

学科分类：090603[农学-临床兽医学] 0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the Major Science and Technology Program for Water Pollution Control and Treatment 

主　　题：enrofloxacin Scenedesmus obliquus toxic effects 

摘      要：In this article, the toxic effects of Enrofloxacin （ENFX） on Scenedesmus obliquus were studied, through investigating the growth, photosynthetic pigments, and protein contents. The possible toxic mechanisms of ENFX were analyzed by determining the superoxide dismutase （SOD） activity, malondialdehyde （MDA） content, proline content, and superoxide anion （O2） generation rate. Results showed that the growth of algae was inhibited by ENFX and the 50% effective concentration （EC50） values for 24, 48, 72, and 96 h of ENFX were 88.39, 63.86, 45.10, and 59.16 mg .L^-1, respectively. After treated with ENFX for 96h, the contents of photosynthetic pigments decreased with the increase of ENFX concentration, the content of soluble protein and the activity of SOD increased and then decreased, and the generation rate of superoxide anion （O2^-） increased continually. The contents of MDA and proline changed little in lower ENFX concentration groups, but increased rapidly when treated with higher concentration groups. These results suggested that ENFX affected the growth ofS. obliquus, and the main toxicity mechanism was that algal cells generated the reactive oxygen species under ENFX stress, and then the reactive oxygen species （ROS） induced the oxidation damages of biologic macromolecules and changed the biomembrane permeability further.