Laparoscopic total colectomy: Does the indication influence the outcome?
Laparoscopic total colectomy: Does the indication influence the outcome?作者机构：Department of Digestive Surgery Centre Hospitalo-Universitaire Lyon Sud Hospices Civils de Lyon EA 3738 Université Claude Bernard Lyon1 Faculté de Médecine Lyon Sud Colorectal Research Unit Basingstoke and North Hampshire Foundation Trust Department of Gastro-enterology Centre Hospitalo-Universitaire Lyon-Sud Hospices Civils de Lyon Digestive Federation Centre Hospitalo-Universitaire Edouard Herriot Hospices Civils de Lyon
出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)
年 卷 期：2011年第3卷第11期
页 面：177-182页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Colectomy Inflammatory bowel disease Laparoscopy Familial adenomatous polyposis Constipation Colonic neoplasms Hereditary nonpolyposis Diverticulosis Treatment outcomes
摘 要：AIM: To assess and compare outcomes of laparoscopic total colectomy performed for a variety of indications. METHODS: Sixty six patients underwent laparoscopic total colectomy for inflammatory bowel disease (IBD) (13) and other diseases (53). Data on demographics, pre and post-operative outcomes were collected ***: Mean operative time was 4.5 h. Conversion rate was 13.6%. Total colectomy performed for IBD was associated with a signifi cantly higher anastomotic leak rate (23.1% vs 1.9%, P 0.05). On univariate analysis, hand sewn anastomosis and treatment with more than 20 mg of prednisolone for at least 3 mo was associated with a higher anastomotic leak rate (P 0.05). No signifi cant difference was found in return of gut function and overall morbidity between disease groups. CONCLUSION: Laparoscopic total colectomy is feasible and outcomes are equivalent whatever the indica- tion, except for anastomotic leak rate which is higher for patients with IBD.
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