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Preliminary study on synergistic combinations of raw honey with gentamicin against Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa of veterinary origin

Preliminary study on synergistic combinations of raw honey with gentamicin against Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa of veterinary origin

作     者:Moussa Ahmed Baghdad Khiati Saad Aissat Noureddine Djebli 

作者机构:Pharmacognosy Api-Phytotherapy LaboratoryMostaganem UniversityMostaganemAlgeria Institute of Veterinary Sciences University Ibn-KhaldounTiaretAlgeria 

出 版 物:《Journal of Coastal Life Medicine》 (海岸生命医学杂志(英文版))

年 卷 期:2015年第5期

页      面:366-369页

学科分类:0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 07[理学] 071005[理学-微生物学] 10[医学] 

基  金:Supported by Project CNEPRU Department of Biology University-Abdelhamid IBN Badis-Mostaganem Algeria(Grant No.N°:F02220120001) 

主  题:Honey Gentamicin Pseudomonas aeruginosa Escherichia coli 

摘      要:Objective:To search for further synergistic combinations of gentamicin and raw honey that might have potential in treating ***:The antibacterial activity and synergistic interaction of raw honey and gentamicin was assessed by using agar well diffusion *** Gram-negative(Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 2154)bacteria were selected for antibacterial activity *** cultures of bacteria were maintained in their appropriate agar slants at 4°C throughout the study and used as stock ***:Raw honey and gentamicin interacted synergistically to inhibit Escherichia coli and Pseudomonas ***:These results suggest that combinations of raw honey and gentamicin have therapeutic benefits in prophylaxis of infections caused by multidrug-resistant Gram-negative bacilli.

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