Application of stem cells in tissue engineering for defense medicine

作     者：Chinedu Cletus Ude Azizi Miskon Ruszymah Bt Hj Idrus Muhamad Bin Abu Bakar 

作者机构：Bio-artifical Organ and Regenerative Medicine UnitNational Defence University of MalaysiaSungai Besi Camp57000 Kuala LumpurMalaysia Department of PhysiologyPre-clinical BlockNational University of Malaysia Medical CentreJalan Yaacob LatifBandar Tun Razak56000 Kuala LumpurMalaysia 

出 版 物：《Military Medical Research》 (军事医学研究（英文版）)

年 卷 期：2018年第5卷第2期

页      面：140-158页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 0836[工学-生物工程] 

基　　金：the Ministry of Higher Education Malaysia(MOHE) National Defence University of Malaysia for the approved FRGS/2/2013/SKK01/UPNM/02/1 and PRGS/2/2015/SKK07/UPNM/02/1 funds 

主　　题：Tissue engineering Defense medicine Stem cells War injuries 

摘      要：The dynamic nature of modern warfare,including threats and injuries faced by soldiers,necessitates the development of countermeasures that address a wide variety of *** engineering has emerged as a field with the potential to provide contemporary *** this review,discussions focus on the applications of stem cells in tissue engineering to address health risks frequently faced by combatants at *** development depends intimately on stem cells,the mysterious precursor to every kind of cell in the body that,with proper instruction,can grow and differentiate into any new tissue or *** reports have suggested the greater therapeutic effects of the anti-inflammatory,trophic,paracrine and immune-modulatory functions associated with these cells,which induce them to restore normal healing and tissue regeneration by modulating immune reactions,regulating inflammation,and suppressing ***,the use of stem cells holds significant promise for the treatment of many battlefield injuries and their *** applications include the treatment of injuries to the skin,sensory organs,nervous system tissues,the musculoskeletal system,circulatory/pulmonary tissues and genitals/testicles and of acute radiation syndrome and the development of novel *** new research developments in these areas suggest that solutions are being developed to reduce critical consequences of wounds and exposures suffered in *** military applications of stem cell-based therapies are already saving the lives of soldiers who would have died in previous *** that would have resulted in deaths previously now result in wounds today;similarly,today’s permanent wounds may be reduced to tomorrow’s bad memories with further advances in stem cell-based therapies.