Prediction of Compressive Strength of Biodegradable Mg–Zn/HA Composite via Response Surface Methodology and Its Biodegradation

作     者：Loy Liang Soon Hussain Zuhailawati Ismail Suhaina Brij Kumar Dhindaw 

作者机构：Structural Materials Niche Area GroupSchool of Materialsand Mineral Resources EngineeringEngineering CampusUniversiti Sains Malaysia14300 Nibong TebalPenangMalaysia School of Minerals Metallurgical and Materials EngineeringIndian Institute of Technology BhubaneswarBhubaneswar751007India 

出 版 物：《Acta Metallurgica Sinica(English Letters)》 (金属学报（英文版）)

年 卷 期：2016年第29卷第5期

页      面：464-474页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：Ministry of High Education(FRGS Grant No.6071304)for the financial support 

主　　题：Powder metallurgy Magnesium-zinc alloy Hydroxyapatite Response surface methodology Biodegradation 

摘      要：This work aimed to fabricate magnesium zinc/hydroxyapatite （Mg-Zn/HA） composite via powder metallurgy method and to develop a mathematical model to predict the compressive strength of the composite using response surface methodology method. The effect of various mechanical milling parameters, milling speed （200-300 r/rain）, ball-to-powder weight ratio （5-12.5） and HA content （2.6-10 wt%） on the compressive strength of Mg-Zn/HA composite was investigated. The model shows that high compressive strength of Mg-Zn/HA composite was achieved when the powders were prepared with high milling speed and ball-to- powder weight ratio and low HA content. The mathematical model was adequate with error percentage lower than 3.4%. The microstructure of Mg-Zn/HA composite with different process parameters revealed that fine microstructure was observed at high milling speed and ball-to-powder weight ratio while agglomeration of HA was found in composite with 10 wt% HA. The agglomeration of HA led to degradation of interfacial bonding strength between matrix and reinforcement phases and hence decreased the overall compressive strength of Mg-Zn/HA composite. Biodegradation test revealed that sample with higher HA content had more weight gain and there was more formation of hydroxyapatite. Mg-Zn/HA composite with 8 wt% HA was found to be the best candidate for implant application because it had considerable compressive strength and good biodegradation properties.