Use of Cladophora glomerata Extract against Multidrug Resistant Bacterial Pathogens
Use of Cladophora glomerata Extract against Multidrug Resistant Bacterial Pathogens作者机构：Department of Biology College of Science University of Mustansiriyah Baghdad 00964 Iraq Department of Biology College of Science University of Baghdad Baghdad 00964 Iraq
出 版 物：《Journal of Environmental Science and Engineering(B)》 (环境科学与工程（B）)
年 卷 期：2013年第2卷第8期
页 面：495-500页
学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1007[医学-药学(可授医学、理学学位)] 12[管理学] 120203[管理学-旅游管理] 1202[管理学-工商管理] 08[工学] 10[医学]
主 题：Cladophora glomerata antimicrobial active compound extracts.
摘 要：The antibacterial effect of the crude methanol extracts and purified fractions of Ctadophora glomerata （Linnaeus） Kutzing （Cladophoraceae） against multidrug resistant human pathogen were investigated. The test bacterial strains were Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus faecalis, Escherichia coli and S. typhimurium. Ethanol extract （0.5 mg/mL） of Cladophora glomerata inhibited growth of all the test organisms. Primary detection of active compounds showed that maeroalgae （Cladophora glomerata） containing flavonoids, alkaloids, phenols and tannins. Gas Chromatography-Mass Spectrometry was used to know the compounds which responsible of antibacterial activity and they were g-Pentadecanone that was found to be a major compound （42.67%） followed by 8-Octadecanone （22.43%） and Salicylic acid （20.04%） in addition to 10-hexadecaden （8.01%）. These findings suggest the possibility of using the Cladophora glomerata as a novel source of natural antimicrobial agents in pharmaceutical industries.
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