Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess
Microwave assisted synthesis of novel Hantzsch 1,4-dihydropyridines,acridine-1,8-diones and polyhydroquinolines bearing the tetrazolo[1,5-α]quinoline moiety and their antimicrobial activity assess作者机构:Department of ChemistrySardar Patel UniversityVallabh Vidyanagar 388120GujaratIndia
出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期:2011年第22卷第12期
页 面:1407-1410页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
主 题:Microwave assisted Tetrazolo[1 5-α]quinoline 1 4-Dihydropyridine Acridine-1 8-dione Polyhydroquinoline Antimicrobial activity
摘 要:Microwave assisted efficient Hantzsch reaction via four-component coupling reactions of tetrazolo[1,5-α]quinoline-4-carbal-dehyde, dimedone/cyclohexane-1,3-dione,ethyl/methyl acetoacetate and ammonium acetate was described as the preparation of tetrazolo[1,5-α]quinoline based 1,4-dihydropyridines,acridine-1,8-diones and *** process presented here is simple,rapid,environmentally welcoming and high *** the derivatives were subjected to an in vitro antimicrobial screening against a representative panel of bacteria and fungi and results worth further investigations.