Function of Rho GTPase Activating Protein 11A in Tumors

作     者：Hui-Nian Zhou Yan-Xian Ren Long Li Ke-Shen Wang Zuo-Yi Jiao Zhou Hui-Nian;Ren Yan-Xian;Li Long;Wang Ke-Shen;Jiao Zuo-Yi

作者机构：Department of General Surgery Lanzhou University Second Hospital Lanzhou University Lanzhou Gansu 730030 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2018年第131卷第11期

页      面：1365-1366页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by grants from the Health Industry Scientific Research Program of Gansu province the Key Research and Development Program of Gansu province 

主　　题：GTPase 编码蛋白质 Rho 激活 肿瘤 cDNA 中心定位 染色体 

摘      要：To the Editor： Rho GTPase Activating Protein 1 IA （ArhGAPllA） is a member of the Rho GTPase-activating proteins （Rho GAPs） gene family and is located on the long arm of 15 chromosome region 1 band 3 subband 2 （ 15q 13.3）. The full-length cDNA of ArhGAPIIA is 24,806 bp with a single open-reading frame. ArhGAPIIA is encoded by 13 exons and the encoded protein has three domains： a RhoGAP domain near the N terminus （amino acids 46-246）, and two uncharacterized domains respectively located in the center （387 516） and C terminus （590-997） of the protein.