Current Perspective in the Discovery of Anti-aging Agents from Natural Products
在从自然产品的反老化代理人的发现的当前的观点作者机构:State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina University of Chinese Academy of SciencesBeijing 100039China Key Laboratory for Aging and Regenerative MedicineDepartment of PharmacologySchool of PharmacySouthwest Medical UniversityLuzhou 646000SichuanChina Guangdong Key Laboratory of Marine Material MedicalSouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301GuangdongChina Yunnan Key Laboratory of Natural Medicinal ChemistryKunming Institute of BotanyChinese Academy of Sciences134 Lanhei RoadKunming 650201YunnanChina
出 版 物:《Natural Products and Bioprospecting》 (应用天然产物(英文))
年 卷 期:2017年第7卷第5期
页 面:335-404页
学科分类:08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程(可授工学、理学学位)]
基 金:the Natural Science Foundation of China(81671405 and 81370453) Natural Science Foundation of Yunnan province(2013FA045 and 2015FB172) Open Funds of Guangdong Key Laboratory of Marine Materia Medica
主 题:Aging Natural products Anti-aging Drug screening
摘 要:Aging is a process characterized by accumulating degenerative damages,resulting in the death of an organism *** main goal of aging research is to develop therapies that delay age-related diseases in *** signaling pathways in aging of Caenorhabditis elegans(***),fruit flies and mice are evolutionarily conserved,compounds extending lifespan of them by intervening pathways of aging may be useful in treating age-related diseases in *** products have special resource advantage and with few side ***,many compounds or extracts from natural products slowing aging and extending lifespan have been *** we summarized these compounds or extracts and their mechanisms in increasing longevity of *** or other species,and the prospect in developing antiaging medicine from natural products.