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Autophagy: a potential target for the treatment of intraocular neovascularization

Autophagy: a potential target for the treatment of intraocular neovascularization

作     者:Xia-Ru Zhu Jun-Hui Du 

作者机构:Department of Ophthalmology Xi'an Ninth Hospital Affiliated to Medical College of Xi'an Jiaotong University 

出 版 物:《International Journal of Ophthalmology(English edition)》 (国际眼科杂志(英文版))

年 卷 期:2018年第11卷第4期

页      面:695-698页

核心收录:

学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基  金:Supported by the Natural Science Foundation of Shaanxi province(No.2016JM8018) the Natural Science Foundation of Xi’an Science Technology Bureau[(No.SF1508(3)] 

主  题:autophagy angiogenesis vascular endothelial growth factor 

摘      要:The formation of neovascularization is a common pathological feature of many ocular vascular diseases, and is an important cause of vision loss in patients. Neovascularization can cause retinal hemorrhage, vitreous hemorrhage, and other serious complications, leading to loss of vision. The treatment of intraocular neovascularization is the focus of ophthalmology research. In recent years, some studies have found that autophagy is closely related to vascular endothelial growth factor and the formation of neovascularization. Autophagy is expected to become a new target for the treatment of intraocular neovascularization. Therefore, this article reviews the research on autophagy and the formation of intraocular neovascularization.

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