Effects of Ficus asperifolia on normal rat estrus cyclicity

作     者：Esther Ngadjui Pierre Watcho Telesphore Benoit Nguelefack Albert Kamanyi 

作者机构：Department of Animal BiologyFaculty of ScienceUniversity of Dschang 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2013年第3卷第1期

页      面：53-57页

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

主　　题：Ficus asperifolia Estrus cycle Rats. 

摘      要：Objective:To evaluate Ficus asperifolia(Moraceae)(***)effecting on regular estrus cycle of Wistar ***:Air-dried fruits of *** were extracted using *** to the test,vaginal smear was monitored daily for a 3-week period to select females with normal(regular)estrous *** with regular estrus cycle weighing between 150-170 g were randomized into three sets of 15 animals *** set was then divided into three groups:Group 1(control)was orally administered with distilled water(10 mL/kg body weight)once a day for 1 week starting from the proestrus *** 2 and 3 were respectively treated with 100and 500 mg/kg body weight of the plant aqueous *** two other sets of 15 animals each were similarly treated as the first set for 3 weeks and 6 weeks *** cycle pattern was monitored before and during plant extract application whereas lipid profile,ovary,uterus and liver growth indices were determined at the end of each ***:*** did not disrupt(0%)the order of appearance of normal estrus cycle stages,namely,proestrus,estrus,metestrus and ***-term treatment(1 week duration)exhibited high frequency of appearance of proestrus and estrus stages while mid-(3 weeks)and long-term(6 weeks)treatments revealed constancy in the frequency of all stages irrespective to animal *** plasma and organ lipid profile,as well as ovary,uterus and liver growth remained unchanged when compared to distilled water-treated *** long-term administration of plant extract(6 weeks),no adverse effect was ***:Our data partially support the use of *** in common medicine.