Antiviral effect of polyphenol rich plant extracts on herpes simplex virus type 1
Antiviral effect of polyphenol rich plant extracts on herpes simplex virus type 1作者机构:Chemistry of Tannins DepartmentNational Research CentreDokki12622 CairoEgypt Chemistry of Natural Compounds DepartmentNational Research CentreDokki12622 CairoEgypt Centre de Rechercheet d’enseignement Yves CoppensCampus de TohannicBP 57356017 VannesFrance
出 版 物:《Food Science and Human Wellness》 (食品科学与人类健康(英文))
年 卷 期:2018年第7卷第1期
页 面:91-101页
核心收录:
学科分类:0832[工学-食品科学与工程(可授工学、农学学位)] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学]
基 金:The authors thank the Academy of Scientific Research&Technology(ASRT Egypt)and Centre de Recherchéet d’enseignement Yves Coppens Campus de Tohannic BP 573 56017 Vannes(France)for supporting this study within the IMHOTEP program(Project No.EGY/FR 8-013)
主 题:Egyptian plants Anti-HSV-1 Polyphenols Vero cell
摘 要:Evaluation of the anti-herpetic activity of 25 Egyptian plants extracts was investigated in vitro in this *** antiviral activity against Herpes Simplex Virus type 1(HSV-1)was done on Vero cell lines by cell *** two plants extracts;namely Euphorbia coopire(Euphorbiaceae)and Morus alba(Moraceae)showed potent anti-herpetic activity and six other extracts showed moderate *** contrast,a bioassay monitored phytochemical exploration of these two plants led to the isolation of pure flavonoid *** antiviral activity of the isolated compounds was also examined,among which seven pure compounds namely;7-galloyl catechin,gallic acid,kaempferol 3-O-β-(6″-O-galloyl)-glucopyranoside,quercetin 3-O-β-(6″-O-galloyl)-glucopyranoside,curcumin,quercetin and kaempferol exhibited significant inhibition.