Bilirubin sensor based on CuO-CdO composites deposited in a nafion/glassy carbon electrode matrixes

作     者：Mohammed M.Rahman Mohammad Musarraf Hussain Abdullah M.Asiri 

作者机构：Chemistry DepartmentKing Abdulaziz UniversityFaculty of Science Center of Excellence for Advanced Material Research (CEAMR)King Abdulaziz University 

出 版 物：《Progress in Natural Science:Materials International》 (自然科学进展·国际材料(英文))

年 卷 期：2017年第27卷第5期

页      面：566-573页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0802[工学-机械工程] 

基　　金：funded by Center of Excellence for Advanced Materials Research (CEAMR) at King Abdulaziz University  Jeddah  under grant no. (CEAMR-SG-3-438) 

主　　题：CuO-CdO nanocomposites Bilirubin biosensor Glassy carbon electrode Sensitivity Real sample analysis Health care field 

摘      要：Copper oxide-cadmium oxide nanocomposites(CuO-CdO NCs) were synthesized by solvothermal technique in a basic medium. CuO-CdO NCs were characterized using conventional techniques, such as Fourier Transform Infrared Spectroscopy(FTIR), UV–Visible Spectroscopy(UV/Vis), Field-Emission Scanning Electron Microscopy(FESEM), X-ray electron dispersive spectroscopy(XEDS), X-ray photoelectron spectroscopy(XPS), and powder X-ray diffraction(XRD). A selective and enzyme-less Bilirubin(BLR) sensor was developed with a thin-layer of NCs onto a glassy carbon electrode(GCE, surface area = 0.0316 cm~2) using 5% nafion binders at room conditions. Improved electrochemical performances of higher sensitivity, lower detection limit,linear dynamic range(LDR), and long-term stability of preferred BLR were achieved by a reliable currentvoltage(I-V) approach. The calibration curve was found linear(R~2= 0.9347) in a wide range of BLR concentration(10.0 pM ~ 10.0 mM). Based on the signal to noise ratio value of 3, the sensitivity and limit of detection(LOD) of the sensor were calculated as 95.0 pA μM-1cm-2and 1.0 ± 0.1 pM *** synthesized CuO-CdO NCs/GCE is an excellent advancement of developing a selective and sensitive BLR sensor by electrochemical approach and practically implemented in real sample applications.