Electrospun multifunctional tissue engineering scaffolds

作     者：Chong WANG Min WANG 

作者机构：Department of Mechanical Engineering The University of Hong Kong Pokfulam Road Hong Kong China 

出 版 物：《Frontiers of Materials Science》 (材料学前沿（英文版）)

年 卷 期：2014年第8卷第1期

页      面：3-19页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：supported by the Hong Kong Research Grants Council through GRF grants 

主　　题：electrospinning monocomponent multicomponent scaffold corHhell drug biomolecule growth factor controlled release 

摘      要：Tissue engineering holds great promises in providing successful treat- ments of human body tissue loss that current methods are unable to treat or unable to achieve satisfactory clinical outcomes. In scaffold-based tissue engineering, a high- performance scaffold underpins the success of a tissue engineering strategy and a major direction in the field is to create multifunctional tissue engineering scaffolds for enhanced biological performance and for regenerating complex body tissues. Electrospinning can produce nanofibrous scaffolds that are highly desirable for tissue engineering. The enormous interest in electrospinning and electrospun fibrous structures by the science, engineering and medical communities has led to various developments of the electrospinning technology and wide investigations of eiectrospun products in many industries, including biomedical engineering, over the past two decades. It is now possible to create novel, multicomponent tissue engineering scaffolds with multiple functions. This article provides a concise review of recant advances in the R ＆ D of electrospun multifunctional tissue engineering scaffolds. It also presents our philosophy and research in the designing and fabrication of electrospun multicomponent scaffolds with multiple functions.