Idiosyncratic Drug-Induced Liver Injury Linked to Polygonum multiflorum:A Case Study by Pharmacognosy

作     者：LI Chun-yu HE Qin GAO Dan LI Rui-yu ZHU Yun LI Hui-fang FENG Wu-wen YANG Mei-hua XIAO Xiao-he WANG Jia-bo 

作者机构：Institute of Medicinal Plant DevelopmentChinese Academy of Medical Sciences & Peking Union Medical College China Military Institute of Chinese Medicine302 Military Hospital School of PharmacyHunan University of Traditional Chinese Medicine School of PharmacyShanxi University of Traditional Chinese Medicine 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2017年第23卷第8期

页      面：625-630页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 10[医学] 100602[医学-中西医结合临床] 

基　　金：Supported by the Being Nova Program(No.Z16111000490000) China's Post-Doctoral Science Fund(No.2016M590065) Beijing Natural Science Foundation(No.7152142) 

主　　题：Idiosyncratic Drug-Induced Liver Injury Linked to Polygonum multiflorum:A Case Study by Pharmacognosy UHPLC DILI 

摘      要：The use of Chinese medicinal herbs（CMH）continues to expand rapidly across the world with a deep belief that herbs are safe because they are＂natural＂.（1）However,a survey of the literature indicates that CMH related hepatotoxicity is increasing and has been a worldwide problem.（2,3）Polygonum multiflorum Thunb.（P.multiflorum）,officially listed in the Pharmacopoeia of the People＇s Republic of China.