“Smart”nanomaterials for cancer therapy

作     者：LE GUYADER Laurent 

作者机构：Chinese Academy of Sciences Key Laboratory for Biological Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2010年第53卷第11期

页      面：2241-2249页

核心收录：

学科分类：1002[医学-临床医学] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the Ministry of Science and Technology of China (2011CB933401 & 2010CB934004) the National Natural Science Foundation of China (31070854) the Knowledge Innovation Program of the Chinese Academy of Sciences (KJCX2-YW-M02) 

主　　题：nanotechnology nanomaterials nanocarrier cancer therapy drug delivery passive target active target 

摘      要：Recent development in nanotechnology has provided new tools for cancer therapy and *** of their small size,nanoscale devices readily interact with biomolecules both on the cell surface and inside the ***,such as fullerenes and their derivatives,are effective in terms of interactions with the immune system and have great potential as anticancer ***,other nanomaterials are able to load active drugs to cancer cells by selectively using the unique tumor environment,such as their enhanced permeability,retention effect and the specific acidic *** and multiplexed nanoparticles,as the next generation of nanoparticles,are now being extensively investigated and are promising tools to achieve personalized and tailored cancer treatments.