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Cystic echinococcosis of the liver: A primer for hepatologists

Cystic echinococcosis of the liver: A primer for hepatologists

作     者:Francesca Rinaldi Enrico Brunetti Andreas Neumayr Marcello Maestri Samuel Goblirsch Francesca Tamarozzi 

作者机构:Division of Infectious and Tropical Diseases San Matteo Hospital Foundation 27100 Pavia Italy Department of Clinical Surgical Diagnostic and Paediatric Sciences University of Pavia WHO Collaborating Centre for the Clinical Management of Cystic Echinococcosis 27100 Pavia Italy Swiss Tropical and Public Health Institute 4002 Basel Switzerland University of Basel 4003 Basel Switzerland Division of General Surgery University of Pavia San Matteo Hospital Foundation 27100 Pavia Italy Emergency Medicine Winona Health Services Winona MN 55987 United States 

出 版 物:《World Journal of Hepatology》 (世界肝病学杂志(英文版)(电子版))

年 卷 期:2014年第6卷第5期

页      面:293-305页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:Supported by The EU grant FP7/2007-2013 No.602051-HERACLES(to Brunetti E) 

主  题:Cystic echinococcosis Hydatidosis Clinical management Diagnosis Treatment Surgery Albenda-zole Watch-and-wait Follow-up Percutaneous treatment 

摘      要:Cystic echinococcosis(CE) is a complex, chronic and neglected disease with a worldwide distribution. The liver is the most frequent location of parasitic cysts. In humans, its clinical spectrum ranges from asymptom-atic infection to severe, potentially fatal disease. Four approaches exist in the clinical management of CE: surgery, percutaneous techniques and drug treatment for active cysts, and the watch and wait approach for inactive cysts. Allocation of patients to these treat-ments should be based on cyst stage, size and location, available clinical expertise, and comorbidities. However, clinical decision algorithms, efficacy, relapse rates, and costs have never been properly evaluated. This paper reviews recent advances in classification and diagnosisand the currently available evidence for clinical deci-sion-making in cystic echinococcosis of the liver.

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