How crystal configuration affects the position detection accuracy in pixelated molecular SPECT imaging systems?

作     者：Hojjat Mahani Gholamreza Raisali Alireza Kamali-Asl Mohammad Reza Ay 

作者机构：Radiation Application Research School Nuclear Science and Technology Research Institute Tehran Iran Research Center for Molecular and Cellular Imaging Tehran University of Medical Science Tehran Iran Radiation Medicine Department Shahid Beheshti UniversityTehran Iran Department of Medical Physics and Biomedical EngineeringTehran University of Medical Science Tehran Iran 

出 版 物：《Nuclear Science and Techniques》 (核技术（英文）)

年 卷 期：2017年第28卷第4期

页      面：24-30页

核心收录：

学科分类：082704[工学-辐射防护及环境保护] 08[工学] 0807[工学-动力工程及工程热物理] 0827[工学-核科学与技术] 0703[理学-化学] 0702[理学-物理学] 0801[工学-力学（可授工学、理学学位）] 

基　　金：supported by Research Center for Molecular and Cellular Imaging(RCMCI) Tehran University of Medical Sciences(No.29885) 

主　　题：Monte Carlo GATE Molecular SPECT Position detection accuracy Pixelated crystal 

摘      要：It is well known that inter-crystal scattering and penetration(ICS-P) are major spatial resolution limiting parameters in dedicated SPECT scanners with pixelated *** this study,the effect of ICS-P on crystal identification in different crystal configurations was evaluated using GATE Monte Carlo simulation.A ^(99m)Tc pencil-beam toward central crystal element was *** incident angle was assumed to vary from 0° to 45° in 5° *** effects of various crystal configurations such as pixel-size,pixel-gap,and crystal material were *** influence of photon energy on the crystal identification(CI) was also *** detection accuracy(PDA) was defined as a factor indicating performance of the ***,a set of ^(99m)Tc point-source simulations was performed in order to calculate peak-to-valley(PVR) ratio for each *** results show that the CsI(Na)manifests higher PDA than NaI(TI) and YAP(Ce).In addition,as the incident angle increases,the crystal becomes less accurate in positioning of the *** a crystal-dependent critical angle,the PDA monotonically *** PDA reaches 0.44 for the CsI(Na) at 45° beam *** PDAs obtained by the point-source evaluation also behave the same as for the pencil-beam *** addition,the PVRs derived from flood images linearly correlate their corresponding *** conclusion,quantitative assessment of ICS-P is mandatory for scanner design and modeling the system matrix during iterative reconstruction algorithms for the purpose of resolution modeling in ultra-high-resolution SPECT.