Neurological and neuropsychological consequences of electrical and lightning shock： review and theories of causation

作     者：Christopher J.Andrews Andrew D.Reisner 

作者机构：Faculty of Medicine-The University of QueenslandHerstonAustraliaLightning and Electrical InjuriesMt Ommaney Family PracticeMt OmmaneyBrisbaneAustralia Forensic Diagnostic Center of District NineCambridgeOHUSA 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2017年第12卷第5期

页      面：677-686页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

主　　题：electrical injury lightning injury neurology neuropsychology neuropsychiatry injury trauma 

摘      要：Injuries from lightning and electrical injuries involve multiple systems of the body, however neurological symptoms are very widely reported. A disabling neuropsychological syndrome is also noted. This paper presents a comprehensive review of neurological and neuropsychological symptoms. Partial theories of causation for these injuries have been advanced, however, there is no convincing explanation for both delay in onset of symptoms and also the genesis of the neuropsychological syndrome. A theory of causation is proposed which satisfies both these constraints. This theory suggests circulating hormones such as cortisol, together with nitric oxide and oxidant free radicals from glutamatergic hyper-stimulation, act on tissues remote from the injury path including the hippocampus. This theory opens a research path to explore treatment options.