Synthesis of epichlorohydrin from 1,3-dichloropropanol using solid base

作     者：Yangcheng Lu Tianyang Li Rui Wang Guangsheng Luo 

作者机构：State Key Laboratory of Chemical Engineering Department of Chemical EngineeringTsinghua UniversityBeijing 100084China 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2017年第25卷第3期

页      面：301-305页

核心收录：

学科分类：081702[工学-化学工艺] 081705[工学-工业催化] 08[工学] 0817[工学-化学工程与技术] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：Supported by the National Natural Science Foundation of China(21176136,21422603) the National Science and Technology Support Program of China(2011BAC06B01) 

主　　题：Clean processes Reaction Process design Kinetics Multiphase 

摘      要：In this work, the synthesis of epichlorohydrin(ECH) from 1,3-dichloropropanol(DCP) by using solid sodium hydroxide(NaOH) is carefully investigated. Inert organic solvent, 1-octanol, is introduced to ensure reaction intensity under control. The reaction performances with respect to apparent kinetics and selectivity are determined to explore optimized reaction conditions and confirm potentials for enhancing productivity in one batch. The dissolution and liquid phase reaction mechanism and instant reaction assumption are proposed and verified through process analysis. A process design towards free additional water is schematically figured out to manipulate solid NaOH, by-product,and unreacted starting materials to realize a nearly closed circuit. This process allows high selectivity over 97% and complete DCP conversion at 323.2 K within a reaction time less than 20 min. Other advantages include near-zero wastewater emission, economically possible NaOH regeneration from NaCl, and robust operating condition window.