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Impact of Hypertension on Type 2 Diabetes in Mysore Population of South India

Impact of Hypertension on Type 2 Diabetes in Mysore Population of South India

作     者:Mohammed Salman Shruti Dasgupta Cletus J. M. D’Souza D. Xaviour B. V. Raviprasad Jayashankar Rao G. L. Lakshmi 

作者机构:Anthropological Survey of India Southern Regional Centre Mysore India Anthropological Survey of India Southern Regional Centre Mysore India Department of Studies in Biochemistry University of Mysore Mysore India Anthropological Survey of India Southern Regional Centre Mysore India Department of Studies in Biotechnology University of Mysore Mysore India 

出 版 物:《International Journal of Clinical Medicine》 (临床医学国际期刊(英文))

年 卷 期:2013年第4卷第12期

页      面:561-570页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Hypertension Type 2 Diabetes Prevalence Kidney Dysfunction Mortality Mysore Population India 

摘      要:Objective: The study aims to explore the prevalence of hypertension and its impact on Type 2 diabetes in a Mysore population of the Indian subcontinent. Methods: 636 participants volunteered for the study. Anthropometric measurements and blood pressure were recorded while plasma was analyzed for biochemical markers. The IDF and JNC 7 diagnostic criteria were followed to define diabetes and hypertension. Statistical Analyses: One-way analysis of variance, χ2-test and Logistic regression analysis were performed to assess differences of the mean, proportion and the independent effect of hypertension on the development of type 2 diabetes. Results: Hypertension was observed to be prevalent in 37.1% of the studied population with an insignificant gender difference. Rate of occurrence of hypertensives was found to be significantly higher in type 2 diabetes (51.9%), obese subjects (45.2%), long-term smokers (49%) and alcohol addicts (48%) than control groups. The risk of development of diabetes was significantly higher in hypertensives than normotensive. However, when creatinine and blood urea nitrogen were included in the model, the significance was nullified. Conclusions: The prevalence of type 2 diabetes and hypertension is increasing at an alarming rate. This study reveals that the significance of hypertension as a parameter in predicting the risk of type 2 diabetes was influenced by the renal function and lipid profile.

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