Retinal vessel oxygen saturation in healthy subjects and early branch retinal vein occlusion

作     者：Jing-Yan Yang Bing You Qian Wang Szy Yann Chan Jost B.Jonas Wen-Bin Wei 

作者机构：Beijing Tongren Eye CenterBeijing Tongren HospitalBeijing Ophthalmology and Visual Science Key LabCapital Medical UniversityBeijing 100730China Department of OphthalmologyMedical Faculty Mannheim of the Ruprecht-Karls-UniversityMannheim 69047Germany Beijing Key Laboratory of Intraocular Tumor Diagnosis and TreatmentBeijing 100730China 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2017年第10卷第2期

页      面：267-270页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：Supported by National Natural Science Foundation of China(No.81570891 No.81272981) the Beijing Municipal Administration of Hospitals’Ascent Plan(No.DFL20150201) Science&Technology Project of Beijing Municipal Science&Technology Commission(No.Z151100001615052) Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support(No.ZYLX201307) Beijing Natural Science Foundation(No.7151003) Advanced Health Care Professionals Development Project of Beijing Municipal Health Bureau(No.2014-2-003) 

主　　题：ischemia retinal oxygen saturation branchretinal vein occlusion retinal oximetry 

摘      要：AIM： To measure the retinal oxygen saturation in healthy subjects and early branch retinal vein occlusion（BRVO） in Chinese ***： The retinal vessel oxygen saturation of the healthy subjects and BRVO patients were measured by a noninvasive retinal oximeter（Oxymap ehf.,Reykjavik,Iceland）.RESULTS： The study included 22 patients with unilateral BRVO（mean age： 55.1±8.8y） in the study group and 91 healthy participants（mean age： 37.5±14.0y） in the control *** the healthy individuals,mean arterial and venous oxygen saturation were significantly（P〈0.001）higher in the superior nasal quadrant（98.5%±10.1%and 57.3%±8.7%,respectively） than in the inferior nasal quadrant（94.2%±9.0% and 54.1%±9.6%,respectively）,followed by the superior temporal quadrant（89.1%±10.1%and 51.9%±8.9%,respectively） and the inferior temporal quadrant（86.4%±9.4% and 46.6%±9.6%,respectively）.In patients with ischemic BRVO,arterial oxymetric values were significantly higher and venous measurements significantly lower for the affected vessel（107.5%±9.7% and46.4%±14.2%,respectively） than the unaffected vessel in the same eye（99.2%±12.2% and 55.5%±7.9%,respectively）and as compared to the vessel in the unaffected fellow eye（93.1%±6.9% and 55.7%±6.8%）（P=0.005 and P=0.02,respectively）.In the patients with non-ischemic BRVO,mean venous oxygen saturation was lower in the affected vein（39.8%±12.2%） than in the unaffected vessels of the same eye（50.8%±10.5%） and in the fellow eye（58.21%±5.7%）（P=0.03）.Mean arterial oxygen saturation did not differ significantly（P=0.42） between all three ***： In patients with BRVO,the venous oxygen saturation in the affected vessels is decreased potentially due to decreased blood velocity and ***,thearterial oxygen saturation in eyes with ischemic BRVO is increased in the affected arteries.