Study of Coronary Artery Disease in Single Aortic Valvular Disease

作     者：张斌 杨伟民 占亚平 

作者机构：Department of Cardiology Guangdong Cardiovascular Institute Guangzhou 510100 P R China Department of Cardiology Guangdong Gaoyao Municipal People' s hospital Gaoyao 526040 P R China Department of Cardiology Jiangxi Jingdezhen First Municipal People's Hospital Jingdezhen 333000 P R Chinabjectives To analyze the results of coronary angiographies (CAG) in patients with single aortic valvular heart disease To study the relationship between aortic valve diseases and coronary artery disease (CAD). Methods 105 patients with single aortic valvular heart disease before surgery underwent angiography. The data of clinical characteristics and angiographies were analyzed. Results 51 patients had symptoms of angina pectoris among 105 patients with single aortic valvular heart disease. Seven of them were confirmed coronary artery disease by angiographies. Although the incidence of angina in aortic valve stenosis group was significantly higher than that in aortic valve regurgitation the probability of combination of CAD in aortic valve stenosis group was similar to the later. However the probability of combination of CAD in degenerative aortic valve group was significantly higher than the groups of rheumatic congenitally bicuspid aortic valves and other causes (p < 0.01 ). Conclusions Angina pectoris is not sensitive for diagnosis of CAD in single aortic valve heart disease. The probability of combination of CAD in degenerative aortic valve disease is higher than that in aortic valve disease with other causes. Coronary angiography is strongly suggested for these patients. 

出 版 物：《South China Journal of Cardiology》 (岭南心血管病杂志（英文版）)

年 卷 期：2003年第4卷第2期

页      面：75-76,86页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Valvular heart disease Coronary artery disease Coronary angiography 

摘      要：Objectives To analyze the results of coronary angiographies (CAG) in patients with single aortic valvular heart disease; To study the relationship between aortic valve diseases and coronary artery disease (CAD). Methods 105 patients with single aortic valvular heart disease before surgery underwent angiography. The data of clinical characteristics and angiographies were analyzed. Results 51 patients had symptoms of angina pectoris among 105 patients with single aortic valvular heart disease. Seven of them were confirmed coronary artery disease by angiographies. Although the incidence of angina in aortic valve stenosis group was significantly higher than that in aortic valve regurgitation, the probability of combination of CAD in aortic valve stenosis group was similar to the later. However, the probability of combination of CAD in degenerative aortic valve group was significantly higher than the groups of rheumatic, congenitally bicuspid aortic valves, and other causes (p 0.01 ). Conclusions Angina pectoris is not sensitive for diagnosis of CAD in single aortic valve heart disease. The probability of combination of CAD in degenerative aortic valve disease is higher than that in aortic valve disease with other causes. Coronary angiography is strongly suggested for these patients.