Giant molecules:where chemistry,physics,and bio-science meet

作     者：Guang-Zhong Yin Wen-Bin Zhang Stephen Z.D. Cheng 

作者机构：Key Laboratory of Polymer Chemistry & Physics of Ministry of EducationCenter for Soft Matter Science and EngineeringCollege of Chemistry and Molecular EngineeringPeking University College of Polymer Science and Polymer EngineeringThe University of Akron 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2017年第60卷第3期

页      面：338-352页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(21674003,21474003,91427304) the National High Technology Research and Development Program of China(2015AA020941) the National Science Foundation of US (DMR-0906898,DMR-1409972) 

主　　题：giant molecules molecular nanoparticles protein protein engineering domains 

摘      要：This feature article focuses on the recent development of giant molecules,which has emerged at the interface among chemistry,physics,and *** molecular designs are inspired by natural polymers like proteins and are modularly constructed from molecular nanoparticle building blocks via sequential click *** important molecular parameters such as topology,composition,and molecular weight can be precisely *** hierarchical assembly reveals many features reminiscent of both small molecules and proteins yet unusual for conventional synthetic *** features are summarized and compared along with synthetic polymers and ***,examples are given in each category of giant molecules to illustrate the characteristics of their hierarchical assembly across different length,time and energy *** idea of artificial domain is presented in analogy to the structural domains in *** doing so,we aim to develop a rational and modular approach toward functional *** factors that dominate the materials functions are discussed with respect to the precision and dynamics of the *** complexity of structure-function relationship is acknowledged,which suggests that there is still a long way to go toward the convergence of synthetic polymers and biopolymers.