日本血吸虫模拟虫卵抗原的初步研究

作     者：钱旻 白艳军 章平 吴自荣 严自助 QIAN Min;BAI Yan-jun;ZHANG Ping;WU Zi-rong;YAN Zi-zhu

作者机构：华东师范大学生物系上海200062 中国预防医学科学院寄生虫病研究所上海200025 

出 版 物：《中国寄生虫学与寄生虫病杂志》 (Chinese Journal of Parasitology and Parasitic Diseases)

年 卷 期：2000年第18卷第5期

页      面：312-313页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

基　　金：国家"九五"攻关项目!资助 (No .96 90 6 0 4 0 4) 

主　　题：日本血吸虫 虫卵抗原 模拟 噬菌体 外源多肽 

摘      要：The egg of Schistosoma japonicum is a chief pathogenic factor. The preparation of egg antigen is a troublesome work, and needs a large number of experimental animals. In order to explore and develop an egg mimotope that can be used in the study of diagnostic reagents and vaccines, we employed the phage display random 15-peptides library to mimic the antigen epitope recognized by mAb 6B12 which is specific to egg antigen of Schistosoma japonicum.