ZINC DEPLETION IN SEVERE PRE-ECLAMPSIA

作     者：吴军 刘棣临 周建德 

作者机构：Department of Obstetrics & Gynecology Perinatal Division SSMU Shanghai Shanghai Institute of Pediatrics Xinhua Hospital 

出 版 物：《Medical Bulletin of Shanghai Jiaotong University》 (上海交通大学学报(医学英文版))

年 卷 期：1987年第2期

页      面：62-68页

主　　题：zinc metabolism pre eclampsia fetal growth 

摘      要：52 cases with severe pre-eclampsia were studied prospectivelyfor the probable relationship between zinc metabolism and pregnancy-induced hypertension. Zinc level of maternal blood in the study group was significantly lower than that in the non-hypertensive control group (P0.01). A positive correlation was found btween zinc level in cord blood and newborn’s weight. The lower the maternal plasma zinc concentration is, the earlier the development of the disease (r=0.76, P0.001); the larger the amount of protein in urine and the lower the zinc level in the cord blood of their fetuses will be. The disease would affect maternal zinc level and improvement of maternal zinc status might benefit the augmentation of zinc levels in the fetuses. It is only when the exhaustion status of zinc to some degree that the growth of the fetus would be involved.