HEMOGLOBIN BEIJING [α16(A14)Lys→Asn]——A NEW FAST MOVING HEMOGLOBIN VARIANT
HEMOGLOBIN BEIJING [α16(A14)Lys→Asn]——A NEW FAST MOVING HEMOGLOBIN VARIANT作者机构:Institute of Basic Medical seiences Chinese Academy of Medical Sciences Beijing Beijing Friendship HosPital
出 版 物:《Chinese Science Bulletin》 (A Monthly Journal of Science)
年 卷 期:1983年第28卷第10期
页 面:1432-页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:hemoglobin donor cellulose substituted acetate A14)Lys Asn district FAST Family
摘 要:A fast moving hemoglobin variant with a mobility similar to that of HbJ, being between HbA and Hb Bart’s, was detected with cellulose acetate eleetrophoresis from a blood donor in Beijing Friendship Hospital. Structural analysis demonstrated that its a16 Lysine is substituted by Asparagine, and that the variant is not previously reported in the literature. It was thus named Hb Beijing, according to the district where it was first found, and is expressed as