The Distribution of the 5-hydroxytryptamin(5-HT) Immunoreactive Cells in the Pancreas of Guinea-pig
The Distribution of the 5-hydroxytryptamin(5-HT) Immunoreactive Cells in the Pancreas of Guinea-pig作者机构:Department of Histology and Embryology Fourth Military Medical University Xi'an
出 版 物:《Journal of Medical Colleges of PLA(China)》 (中国人民解放军军医大学学报(英文版))
年 卷 期:1989年第4卷第3期
页 面:239-242页
学科分类:10[医学]
主 题:serotonin immunochemistry pancrcas guinea-pig
摘 要:Immunocytochemical localization of 5-hydroxytryptamine (5-HT) containing cells of the guinea-pig pancreas was studied by means of PAP-glucose oxidase-DAB-nickel (PAP-GDN) and PAPstaining methods on paraffin sections. In this study we demonstrated the presence of 5-HTimmunoreactive cells in the endocrine (islets) and exocrine pancreas of the guinea-ping. Cells exhib-iting 54-HT immunoreactivity were found in the center and the periphery of the pancreatic islets. The5-HT immunoreactive granules were evenly distributed throughout the cytoplasm, but was faint inthe nuclei. Cells of this type were also distributed in the exocrine pancreas. Grouped or single or single cellsoccurred intercalatedly between acinar cells, as well as in the epithlium of ducts and in the connectivetissues near the ducts or acini.