肌肉特异性酪氨酸激酶抗体与乙酰胆碱受体抗体阳性重症肌无力患者四肢与面肌的单纤维肌电图
Single-fiber electromyography in limb and facial muscles in muscle-specific kinase antibody and acetylcholine receptor antibody myasthenia gravis作者机构：Department of Clinical Neurology University of Oxford Radcliffe Infirmary Oxford United Kingdom
出 版 物：《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals.Clinical Neurology)
年 卷 期：2006年第8期
页 面：33-34页
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
主 题：重症肌无力 神经肌肉疾病 酪氨酸激酶 抗体阳性 乙酰胆碱受体 特异性 患者
摘 要：We examined the findings from single- fiber electromyography in extensor digitorum communis (EDC) and orbicularis oculi (OOc) in 13 myasthenia gravis (MG) patients with musclespecific kinase antibodies (MuSK- MG) and 12 MG patients with acetylcholine receptor antibodies (AChR- MG) with similar clinical scores. More than 70% of AChR- MG patients had abnormal jitter in both EDC and OOc, but the majority of MuSK- MG patients had normal jitter in EDC despite abnormal jitter in OOc. These findings demonstrate clear differences between the neurophysiology of MuSK- MG and AChR- MG.
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