Chemotherapy and drug resistance status of malaria parasite in northeast India

作     者：Diganta Goswami Indra Baruah Sunil Dhiman Bipul Rabha Vijay Veer Lokendra Singh Dhirendra Kumar Sharma 

作者机构：Division of Medical EntomologyDefence Research LaboratoryTezpurAssam.India Directorate of Life SciencesDRDO HQNew DelhiIndia Department of ZoologyGauhati UniversityGuwahatiIndia 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2013年第6卷第7期

页      面：583-588页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

主　　题：Malaria Chemotherapy Antimalarials Drug resistance 

摘      要：India reports the highest number of malaria cases in Southeast Asia,of which Plasmodium falciparum contribute more than half of the cases every *** eastern states of India contribute only 3.96%of country’s population but account for10%of total reported malaria cases.11%of Plasmodium falciparum cases and 20%of malaria related deaths *** India,chloroquine resistance was reported for the first time from northeast region and since then chloroquine treatment failure is being reported from many parts of the *** chloroquine treatment failure has led to change of the drug policy to artemisinin combination therapy as first line of malaria treatment in the ***,replacing chloroquine to artemisinin combination therapy has not shown significant difference in the overall malaria incidence in the region,The present review addresses the current malaria situation of northeastern region of India in the light of antimalarials drug resistance.