Study of the Reaction of 5-Aryl-7-hydrazino-2-phenylpyra- zolo[1,5-c]pyrimidines with 1,3-Dicarbonyl Compounds
Study of the Reaction of 5-Aryl-7-hydrazino-2-phenylpyra- zolo[1,5-c]pyrimidines with 1,3-Dicarbonyl Compounds作者机构:Chemistry Department Faculty of Science Alexandria University lbrahimia P. O. Box 426 Alexandria 21321 Egypt
出 版 物:《Chinese Journal of Chemistry》 (中国化学(英文版))
年 卷 期:2011年第29卷第11期
页 面:2451-2460页
核心收录:
学科分类:083001[工学-环境科学] 0830[工学-环境科学与工程(可授工学、理学、农学学位)] 08[工学] 0805[工学-材料科学与工程(可授工学、理学学位)] 080502[工学-材料学]
主 题:cyclization electrophilic substitution pyrazolylpyrazolopyrimidine IR NMR mass spectrometry
摘 要:A novel synthetic method for the preparation of 5-aryl-7-(3,5-dimethyl-lH-pyrazol-l-yl)-2-phenylpyra- zolo[1,5-c]-pyrimidines and 1-(5-aryl-2-phenylpyrazolo[1,5-c]pyrimidin-7-yl)-3-methyl-lH-pyrazol-5-ols is provided by condensative cyclization of 5-aryl-7-hydrazino-2-phenylpyrazolo[1,5-c]pyrimidines with 1,3-dicarbonyl compounds. The study of the more reactive position for electrophilic substitusion reactions on such ring system was also achieved.