Modification of ubiquitin C-terminal hydrolase L1 by reactive lipid species: role in neural regeneration and diseases of aging
Modification of ubiquitin C-terminal hydrolase L1 by reactive lipid species: role in neural regeneration and diseases of aging作者机构:Geriatric Research Educational and Clinical Center V.A. Pittsburgh Healthcare System
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2016年第11卷第6期
页 面:908-909页
核心收录:
学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金:supported in part by NIH R01 NS37459-15
主 题:ubiquitin proteasome regeneration Ubiquitin hydrolase Modification synaptic neuronal lipid enzymes
摘 要:Role of ubiquitin C-terminal hydrolase L1(UCHL1)in brain function:Ubiquitin is used by a variety of cellular systems to tag proteins for transport to various *** are a number of enzymes in the ubiquitin-proteasome pathway(UPP)that tag abnormally folded proteins with ubiquitin for transport to the proteasome for degradation.