Comparison of lipid profile in different grades of non-alcoholic fatty liver disease diagnosed on ultrasound

作     者：Dhumal Uttareshvar Mahaling Madole Mahesh Basavaraj Aher Jagdish Bika 

作者机构：Assistant Professor in RadiodiagnosisGovernment.Medical College Assistant Professor in BiochemistryMaharashtra Institute of Medical Science and ResearchMedical College Junior Resident in RadiodiagnosisGovernment Medical College 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2013年第3卷第11期

页      面：907-912页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Funded by the department of radiodiagnosis with approval by institutional ethics committce of G.R.Medical College Gwalior Madhya pradesh Indiawith Grant no.-GRM/01/15/2009 

主　　题：Non-alcoholic fatty liver disease(NAFLD) Ultrasonography Lipid profile nonalcoholic steatohepatitis(NASH) 

摘      要：Objective:To detect and compare serum lipid abnormalities in patients diagnosed with different grades of non-alcoholic fatly liver on ***:A total of 70 cases which included 30 males and 40 females,diagnosed as nonalcoholic fatty liver disease(NAFLD)on ultrasound were investigated with serum lipid *** a comparison of lipid abnormalities between different grades of fatty liver diagnosed on ultrasound was done.P value was calculated by using analysis of variance lest(ANOVA)and P value0.05 was considered as statistically ***:Out of 70 cases which were diagnosed as NAFLD on ultrasonography,gradeⅠNAFLD cases were 47.15%,gradeⅡwere 42.85%and gradeⅢwere 10%.The mean age of the patients was49.14 *** to female ratio was 3:*** triglycerides,total cholesterol,LDL and VLDL levels were raised in 67.14%,45.71%34.28%,25.71%of cases *** serum HDL levels were seen in 62.85%of *** statistical analysis we found increasing grades of NAFLD were significantly associated with increasing values of total cholesterol(P value-0.001),LDL(P value-0.000)and VLDL(P value-0.003)and decreasing HDL(P value-0.000).Conclusion:Most of the patients of NAFLD in India is asymptomatic,non-diabetic and *** liver biopsy is the gold standard melhod for diagnosis of NAFLD,Ultrasonography which is non-invasive,simple tool,can be used for the early detection of NAFLD in asymptomatic patients.