Baculovirus as a highly efficient expression vector in insect and mammalian cells
Baculovirus as a highly efficient expression vector in insect and mammalian cells作者机构：Department of Chemical Engineering National Tsing Hua University Hsinchu Taiwan China
出 版 物：《Acta Pharmacologica Sinica》 (中国药理学报(英文版))
年 卷 期：2005年第26卷第4期
页 面：405-416页
核心收录：
学科分类：0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种]
基 金：The author gratefully acknowledges the financial support of the National Science Council(Grant NSC 93-2214-E007-016) Ministry of Economic Affairs(Technology Development Program for Academia Grant 93-EC-17A-17S1-0009) Taiwan,China
主 题：baculovirus insect cell mammalian cell gene therapy vaccine recombinant protein
摘 要：Baculovirus has been widely used for the production of recombinant proteins ininsect *** the finding that baculovirus can efficiently transduce mamma-lian cells,the applications of baculovirus have been greatly *** pros-pects and drawbacks of baculovirus-mediated gene expression,either in insect orin mammalian cells,are *** progresses in expanding the applicationsto studies of gene regulation,viral vector preparation,in vivo and ex vivo genetherapy studies,generation of vaccine vectors,etc are discussed and the effortsdirected towards overcoming the existing bottlenecks are particularly emphasized.
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