Mannose-binding lectin 2 rs11003123 polymorphism is associated with the development of hepatocellular carcinoma in patients with hepatitis B-related cirrhosis in the Chinese population

作     者：Pu-Sen Wang Jing Kuai Hao Li Chun-Guang Wang Bao-Jie Shi Lin Zhong 

作者机构：Department of General SurgeryShanghai General HospitalShanghai Jiaotong University School of Medicine Department of Hepatobiliary SurgeryWeifang People’s Hospital 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2016年第15卷第3期

页      面：282-288页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100214[医学-肿瘤学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported in part by grants from the National Natural Science Foundation of China(81170447) the Natural Science Foundation of Shanghai(13JC1404600) the Shanghai Committee for Science&Technology Project(094119524) 

主　　题：mannose-binding lectin 2 polymorphism hepatitis B cirrhosis hepatocellular carcinoma 

摘      要：BACKGROUND： Mannose-binding lectin 2 （MBL2） plays a key role in the host immune response, but whether it is associ- ated with hepatocellular carcinoma （HCC） is not dear. The present study aimed to identify the association between MBL2 gene polymorphisms and HCC in patients with hepatitis B virus （I-IBV）-related cirrhosis in the Chinese population.