Structure and Function of the NS1 Protein of Influenza A Virus

作     者：Dongzi LIN~1 Jingfang LAN~2 Zhizhen ZHANG~1* 1 Department of Biochemistry and Molecular Biology,Guangdong Medical College,Zhanjiang 524023,China 2 Department of Clinical Laboratory,Hejin People's Hospital,Hejin 043300,China 

作者机构：Department of Biochemistry and Molecular Biology Guangdong Medical CollegeZhanjiang 524023 China Department of Clinical Laboratory Hejin People's HospitalHejin 043300 China 

出 版 物：《Acta Biochimica et Biophysica Sinica》 (生物化学与生物物理学报(英文版))

年 卷 期：2007年第39卷第3期

页      面：155-162页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 07[理学] 071005[理学-微生物学] 10[医学] 

主　　题：influenza A virus NS1A protein RNA-binding domain effector domain dimer resistance antiviral response 

摘      要：The avian influenza A virus currently prevailing in Asia causes fatal pneumonia and multipleorgan failure in birds and *** intensive research,understanding of the characteristics of influenzaA virus that determine its virulence is ***1A protein,a non-structural protein of influenza Avirus,was reported to contribute to its pathogenicity and ***1A protein is a multifunctionalprotein that plays a significant role in resisting the host antiviral response during the influenza *** briefly outlines the current knowledge on the structure and function of the NS1A protein.